Pyruvate carboxylase and cancer progression

Pyruvate carboxylase (PC) is a mitochondrial enzyme that catalyzes the ATP-dependent carboxylation of pyruvate to oxaloacetate (OAA), serving to replenish the tricarboxylic acid (TCA) cycle. In nonmalignant tissue, PC plays an essential role in controlling whole-body energetics through regulation of...

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Detalhes bibliográficos
Publicado no:Cancer Metab
Main Authors: Kiesel, Violet A., Sheeley, Madeline P., Coleman, Michael F., Cotul, Eylem Kulkoyluoglu, Donkin, Shawn S., Hursting, Stephen D., Wendt, Michael K., Teegarden, Dorothy
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8088034/
https://ncbi.nlm.nih.gov/pubmed/33931119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40170-021-00256-7
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