Inhibition of pyruvate carboxylase by 1α,25-dihydroxyvitamin D promotes oxidative stress in early breast cancer progression

Maintaining reductive-oxidative (redox) balance is an essential feature in breast cancer cell survival, with cellular metabolism playing an integral role in maintaining redox balance through its supply of reduced NADPH. In the present studies, the effect of 1,25-dihydroxyvitamin D (1,25(OH)(2)D) on...

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Publicat a:Cancer Lett
Autors principals: Wilmanski, Tomasz, Zhou, Xuanzhu, Zheng, Wei, Shinde, Aparna, Donkin, Shawn S., Wendt, Michael, Burgess, John R., Teegarden, Dorothy
Format: Artigo
Idioma:Inglês
Publicat: 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5763507/
https://ncbi.nlm.nih.gov/pubmed/29024812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2017.09.045
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