QTc prolongation during ciprofloxacin and fluconazole combination therapy: prevalence and associated risk factors

AIM(S): Ciprofloxacin and fluconazole combination therapy is frequently used as prophylaxis for, and treatment of, infections in patients with haematological malignancies. However, both drugs are known to prolong the heart rate‐corrected QT (QTc) interval, which is a serious risk factor for torsade...

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Udgivet i:Br J Clin Pharmacol
Main Authors: Berger, Florine A., Monadian, Nico, de Groot, Natasja M. S., Santbergen, Bart, van der Sijs, Heleen, Becker, Matthijs L., Broers, Annoek E. C., van Gelder, Teun, van den Bemt, Patricia M. L. A.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2017
Fag:
Drug Safety
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5777440/
https://ncbi.nlm.nih.gov/pubmed/29057492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13457
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