QTc prolongation during ciprofloxacin and fluconazole combination therapy: prevalence and associated risk factors

AIM(S): Ciprofloxacin and fluconazole combination therapy is frequently used as prophylaxis for, and treatment of, infections in patients with haematological malignancies. However, both drugs are known to prolong the heart rate‐corrected QT (QTc) interval, which is a serious risk factor for torsade...

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Dettagli Bibliografici
Pubblicato in:Br J Clin Pharmacol
Autori principali: Berger, Florine A., Monadian, Nico, de Groot, Natasja M. S., Santbergen, Bart, van der Sijs, Heleen, Becker, Matthijs L., Broers, Annoek E. C., van Gelder, Teun, van den Bemt, Patricia M. L. A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2017
Soggetti:
Drug Safety
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5777440/
https://ncbi.nlm.nih.gov/pubmed/29057492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13457
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