Clinically relevant QTc prolongation due to overridden drug–drug interaction alerts: a retrospective cohort study

AIMS: To investigate whether, in patients in whom drug–drug interaction (DDI) alerts on QTc prolongation were overridden, the physician had requested an electrocardiogram (ECG), and if these ECGs showed clinically relevant QTc prolongation. METHODS: For all patients with overridden DDI alerts on QTc...

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Autores principales: van der Sijs, Heleen, Kowlesar, Ravi, Klootwijk, A Peter J, Nelwan, Stefan P, Vulto, Arnold G, van Gelder, Teun
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science Inc 2009
Materias:
Drug Safety
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2675046/
https://ncbi.nlm.nih.gov/pubmed/19523015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2008.03357.x
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