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Mammalian SWI/SNF Complexes in Cancer: Emerging Therapeutic Opportunities
Mammalian SWI/SNF (BAF) chromatin remodeling complexes orchestrate a diverse set of chromatin alterations which impact transcriptional output. Recent whole-exome sequencing efforts have revealed that the genes encoding subunits of mSWI/SNF complexes are mutated in over 20% of cancers, spanning a wid...
Shranjeno v:
| izdano v: | Curr Opin Genet Dev |
|---|---|
| Main Authors: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2017
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5777332/ https://ncbi.nlm.nih.gov/pubmed/28391084 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gde.2017.02.004 |
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