The ATPase module of mammalian SWI/SNF family complexes mediates subcomplex identity and catalytic activity-independent genomic targeting

Perturbations to mammalian SWI/SNF (mSWI/SNF) chromatin remodeling complexes have been widely implicated as driving events in cancer(1). One such perturbation is the dual loss of the SMARCA4 and SMARCA2 ATPase subunits in small cell carcinoma of the ovary, hypercalcemic type (SCCOHT)(2–5), SMARCA4-d...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nat Genet
Egile Nagusiak: Pan, Joshua, McKenzie, Zachary M., D’Avino, Andrew R., Mashtalir, Nazar, Lareau, Caleb A., St. Pierre, Roodolph, Wang, Lu, Shilatifard, Ali, Kadoch, Cigall
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2019
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6755913/
https://ncbi.nlm.nih.gov/pubmed/30858614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41588-019-0363-5
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