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Estrogen-dependent epigenetic regulation of soluble epoxide hydrolase via DNA methylation
To elucidate molecular mechanisms responsible for the sexually dimorphic phenotype of soluble epoxide hydrolase (sEH) expression, we tested the hypothesis that female-specific down-regulation of sEH expression is driven by estrogen-dependent methylation of the Ephx2 gene. Mesenteric arteries isolate...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5776989/ https://ncbi.nlm.nih.gov/pubmed/29295935 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1716016115 |
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