Lymphocytes eject interferogenic mitochondrial DNA webs in response to CpG and non-CpG oligodeoxynucleotides of class C

Circulating mitochondrial DNA (mtDNA) is receiving increasing attention as a danger-associated molecular pattern in conditions such as autoimmunity, cancer, and trauma. We report here that human lymphocytes [B cells, T cells, natural killer (NK) cells], monocytes, and neutrophils derived from health...

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Опубликовано в: :Proc Natl Acad Sci U S A
Главные авторы: Ingelsson, Björn, Söderberg, Daniel, Strid, Tobias, Söderberg, Anita, Bergh, Ann-Charlotte, Loitto, Vesa, Lotfi, Kourosh, Segelmark, Mårten, Spyrou, Giannis, Rosén, Anders
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2018
Предметы:
PNAS Plus
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5776968/
https://ncbi.nlm.nih.gov/pubmed/29295921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1711950115
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