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Synthesis and Evaluation of 2’-Substituted Cyclobutyl Nucleosides and Nucleotides as Potential Anti-HIV Agents
A series of 2’-substituted cyclobutyl nucleoside analogs were efficiently prepared by constructing the core cyclobutyl ring using different [2+2] cycloaddition approaches. The triphosphate derivative of a cyclobutyl nucleoside was also synthesized and evaluated against wild-type and mutant HIV rever...
में बचाया:
| में प्रकाशित: | Bioorg Med Chem Lett |
|---|---|
| मुख्य लेखकों: | , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2007
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5776709/ https://ncbi.nlm.nih.gov/pubmed/17434736 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2007.03.094 |
| टैग : |
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