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Synthesis and Anti-HIV Activity of d- and l-Thietanose Nucleosides
Various d- and l-thietanose nucleosides (22-27, 33-35, 50-52, 58-60) were synthesized from d- and l-xylose. The four-membered thietane ring was efficiently synthesized by the cyclization of 1-thioacetyl-3-mesylate (4/38) under basic conditions. Condensation with various heterocyclic bases was conduc...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2533431/ https://ncbi.nlm.nih.gov/pubmed/16509580 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm050912h |
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