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Enantioselective synthesis and antiviral activity of purine and pyrimidine cyclopentenyl C-nucleosides
The enantiomerically pure carbocyclic purine and pyrimidine C-nucleosides 1–4 were synthesized via the key intermediate, 2,3-(isopropylidenedioxy)-4-(trityloxymethyl)-4-cyclopenten-1-ol (5), which was prepared from d-ribose in eight steps. Synthesized compounds were evaluated as potential antiviral...
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| Udgivet i: | Bioorg Med Chem |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Elsevier Ltd.
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7127144/ https://ncbi.nlm.nih.gov/pubmed/17085053 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2006.10.043 |
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