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SYNTHESIS AND ANTIVIRAL ACTIVITY OF PURINE 2′,3′-DIDEOXY-2′,3′-DIFLUORO-D-ARABINOFURANOSYL NUCLEOSIDES

9-(2′,3′-Dideoxy-2′,3′-difluoro-β-d-arabinofuranosyl)adenine (20), 2-chloro-9-(2′,3′-dideoxy-2,3-difluoro-β-d-arabinofuranosyl)adenine (22), as well as their respective α-anomers 21 and 23, were synthesized by the nucleobase anion glycosylation of intermediate 5-O-benzoyl-2,3-dideoxy-2,3-difluoro-α-...

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Detalhes bibliográficos
Publicado no:Nucleosides Nucleotides Nucleic Acids
Main Authors: Sivets, Grigorii G., Kalinichenko, Elena N., Mikhailopulo, Igor A., Detorio, Mervi A., McBrayer, Tami R., Whitaker, Tony, Schinazi, Raymond F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7732020/
https://ncbi.nlm.nih.gov/pubmed/20183600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15257770903053979
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