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Abnormal Ergosterol Biosynthesis Activates Transcriptional Responses to Antifungal Azoles

Fungi transcriptionally upregulate expression of azole efflux pumps and ergosterol biosynthesis pathway genes when exposed to antifungal agents that target ergosterol biosynthesis. To date, these transcriptional responses have been shown to be dependent on the presence of the azoles and/or depletion...

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Detalles Bibliográficos
Publicado en:Front Microbiol
Autores principales: Hu, Chengcheng, Zhou, Mi, Wang, Wenzhao, Sun, Xianyun, Yarden, Oded, Li, Shaojie
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5776110/
https://ncbi.nlm.nih.gov/pubmed/29387050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2018.00009
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