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Abnormal Ergosterol Biosynthesis Activates Transcriptional Responses to Antifungal Azoles

Fungi transcriptionally upregulate expression of azole efflux pumps and ergosterol biosynthesis pathway genes when exposed to antifungal agents that target ergosterol biosynthesis. To date, these transcriptional responses have been shown to be dependent on the presence of the azoles and/or depletion...

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Dades bibliogràfiques
Publicat a:Front Microbiol
Autors principals: Hu, Chengcheng, Zhou, Mi, Wang, Wenzhao, Sun, Xianyun, Yarden, Oded, Li, Shaojie
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5776110/
https://ncbi.nlm.nih.gov/pubmed/29387050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2018.00009
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