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De-repression of CSP-1 activates adaptive responses to antifungal azoles

Antifungal azoles are the major drugs that are used to treat fungal infections. This study found that in response to antifungal azole stress, Neurospora crassa could activate the transcriptional responses of many genes and increase azole resistance by reducing the level of conidial separation 1 (CSP...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Chen, Xi, Xue, Wei, Zhou, Jun, Zhang, Zhenying, Wei, Shiping, Liu, Xingyu, Sun, Xianyun, Wang, Wenzhao, Li, Shaojie
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4726075/
https://ncbi.nlm.nih.gov/pubmed/26781458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19447
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