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Abnormal Ergosterol Biosynthesis Activates Transcriptional Responses to Antifungal Azoles

Fungi transcriptionally upregulate expression of azole efflux pumps and ergosterol biosynthesis pathway genes when exposed to antifungal agents that target ergosterol biosynthesis. To date, these transcriptional responses have been shown to be dependent on the presence of the azoles and/or depletion...

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Dettagli Bibliografici
Pubblicato in:Front Microbiol
Autori principali: Hu, Chengcheng, Zhou, Mi, Wang, Wenzhao, Sun, Xianyun, Yarden, Oded, Li, Shaojie
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5776110/
https://ncbi.nlm.nih.gov/pubmed/29387050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2018.00009
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