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Abnormal Ergosterol Biosynthesis Activates Transcriptional Responses to Antifungal Azoles

Fungi transcriptionally upregulate expression of azole efflux pumps and ergosterol biosynthesis pathway genes when exposed to antifungal agents that target ergosterol biosynthesis. To date, these transcriptional responses have been shown to be dependent on the presence of the azoles and/or depletion...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Front Microbiol
Prif Awduron: Hu, Chengcheng, Zhou, Mi, Wang, Wenzhao, Sun, Xianyun, Yarden, Oded, Li, Shaojie
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5776110/
https://ncbi.nlm.nih.gov/pubmed/29387050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2018.00009
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