L-Cystine Diamides as L-Cystine Crystallization Inhibitors for Cystinuria

L-Cystine bismorpholide (1a) and L-cystine bis(N′-methylpiperazide) (1b) were seven and twenty-four times more effective than L-cystine dimethyl ester (CDME) in increasing the metastable supersaturation range of L-cystine, respectively, effectively inhibiting L-cystine crystallization. This behavior...

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Detalhes bibliográficos
Publicado no:J Med Chem
Main Authors: Hu, Longqin, Yang, Yanhui, Aloysius, Herve, Albanyan, Haifa, Yang, Min, Liang, Jian-Jie, Yu, Anthony, Shtukenberg, Alexander, Poloni, Laura N., Kholodovych, Vladyslav, Tischfield, Jay A., Goldfarb, David S., Ward, Michael D., Sahota, Amrik
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5774851/
https://ncbi.nlm.nih.gov/pubmed/27409142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.6b00647
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