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Hexokinase II may be dispensable for CD4 T cell responses against a virus infection

Activation of CD4 T cells leads to their metabolic reprogramming which includes enhanced glycolysis, catalyzed through hexokinase enzymes. Studies in some systems indicate that the HK2 isoform is the most up regulated isoform in activated T cells and in this report the relevance of this finding is e...

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Publicat a:PLoS One
Autors principals: Varanasi, Siva Karthik, Jaggi, Ujjaldeep, Hay, Nissim, Rouse, Barry T.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5774810/
https://ncbi.nlm.nih.gov/pubmed/29352298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0191533
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