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Hexokinase II may be dispensable for CD4 T cell responses against a virus infection

Activation of CD4 T cells leads to their metabolic reprogramming which includes enhanced glycolysis, catalyzed through hexokinase enzymes. Studies in some systems indicate that the HK2 isoform is the most up regulated isoform in activated T cells and in this report the relevance of this finding is e...

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Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Varanasi, Siva Karthik, Jaggi, Ujjaldeep, Hay, Nissim, Rouse, Barry T.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5774810/
https://ncbi.nlm.nih.gov/pubmed/29352298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0191533
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