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Azacytidine Treatment Inhibits the Progression of Herpes Stromal Keratitis by Enhancing Regulatory T Cell Function

Ocular infection with herpes simplex virus 1 (HSV-1) sets off an inflammatory reaction in the cornea which leads to both virus clearance and chronic lesions that are orchestrated by CD4 T cells. Approaches that enhance the function of regulatory T cells (Treg) and dampen effector T cells can be effe...

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Библиографические подробности
Опубликовано в: :J Virol
Главные авторы: Varanasi, Siva Karthik, Reddy, Pradeep B. J., Bhela, Siddheshvar, Jaggi, Ujjaldeep, Gimenez, Fernanda, Rouse, Barry T.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2017
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5355591/
https://ncbi.nlm.nih.gov/pubmed/28100624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02367-16
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