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Hexokinase II may be dispensable for CD4 T cell responses against a virus infection

Activation of CD4 T cells leads to their metabolic reprogramming which includes enhanced glycolysis, catalyzed through hexokinase enzymes. Studies in some systems indicate that the HK2 isoform is the most up regulated isoform in activated T cells and in this report the relevance of this finding is e...

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Библиографические подробности
Опубликовано в: :PLoS One
Главные авторы: Varanasi, Siva Karthik, Jaggi, Ujjaldeep, Hay, Nissim, Rouse, Barry T.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5774810/
https://ncbi.nlm.nih.gov/pubmed/29352298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0191533
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