Wird geladen...
CRISPR-mediated TCR replacement generates superior anticancer transgenic T cells
Adoptive transfer of T cells genetically modified to express a cancer-specific T-cell receptor (TCR) has shown significant therapeutic potential for both hematological and solid tumors. However, a major issue of transducing T cells with a transgenic TCR is the preexisting expression of TCRs in the r...
Gespeichert in:
| Veröffentlicht in: | Blood |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society of Hematology
2018
|
| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5774207/ https://ncbi.nlm.nih.gov/pubmed/29122757 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-05-787598 |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|