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JAK inhibitors for the treatment of myeloproliferative neoplasms and other disorders

JAK inhibitors have been developed following the discovery of the JAK2V617F in 2005 as the driver mutation of the majority of non- BCR-ABL1 myeloproliferative neoplasms (MPNs). Subsequently, the search for JAK2 inhibitors continued with the discovery that the other driver mutations ( CALR and MPL) a...

詳細記述

保存先:
書誌詳細
出版年:F1000Res
主要な著者: Vainchenker, William, Leroy, Emilie, Gilles, Laure, Marty, Caroline, Plo, Isabelle, Constantinescu, Stefan N.
フォーマット: Artigo
言語:Inglês
出版事項: F1000 Research Limited 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5773931/
https://ncbi.nlm.nih.gov/pubmed/29399328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.13167.1
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