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JAK Inhibitors and other Novel Agents in Myeloproliferative Neoplasms: Are We Hitting the Target?

The discovery of somatic mutations in the JAK-STAT signaling pathway was a major breakthrough in our understanding of the molecular pathogenesis of the myeloproliferative neoplasms (MPNs) polycythemia vera, essential thrombocytosis, and primary myelofibrosis. This finding led to the development of s...

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Autori principali: Kucine, Nicole, Levine, Ross L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: SAGE Publications 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3573410/
https://ncbi.nlm.nih.gov/pubmed/23556090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2040620711410095
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