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Functional Consequences of Mutations in Myeloproliferative Neoplasms
Driver mutations occur in Janus kinase 2 (JAK2), thrombopoietin receptor (MPL), and calreticulin (CALR) in BCR-ABL1 negative myeloproliferative neoplasms (MPNs). From mutations leading to one amino acid substitution in JAK2 or MPL, to frameshift mutations in CALR resulting in a protein with a differ...
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| 發表在: | Hemasphere |
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| Main Authors: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Lippincott Williams & Wilkins
2021
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8171364/ https://ncbi.nlm.nih.gov/pubmed/34095761 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/HS9.0000000000000578 |
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