Cargando...
Generation and Characterization of Alloantigen-Specific Regulatory T Cells For Clinical Transplant Tolerance
Donor-specific CD4(+)CD127(−)CD25(+)FOXP3(+) regulatory T cells (AgTregs) have the potential to induce clinical transplant tolerance; however, their expansion ex vivo remains challenging. We optimized a novel expansion protocol to stimulate donor-specific Tregs using soluble 4-trimer CD40 ligand (CD...
Gardado en:
| Publicado en: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group UK
2018
|
| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5773708/ https://ncbi.nlm.nih.gov/pubmed/29348660 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-19621-6 |
| Tags: |
Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!
|