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A Phase I Clinical Trial with Ex Vivo Expanded Recipient Regulatory T cells in Living Donor Kidney Transplants

There is considerable interest in therapeutic transfer of regulatory T cells (Tregs) for controlling aberrant immune responses. Initial clinical trials have shown the safety of Tregs in hematopoietic stem cell transplant recipients and subjects with juvenile diabetes. Our hypothesis is that infusion...

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Mathew, James M., H.-Voss, Jessica, LeFever, Ann, Konieczna, Iwona, Stratton, Cheryl, He, Jie, Huang, Xuemei, Gallon, Lorenzo, Skaro, Anton, Ansari, Mohammed Javeed, Leventhal, Joseph R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5943280/
https://ncbi.nlm.nih.gov/pubmed/29743501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-25574-7
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