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Redundancy of protein disulfide isomerases in the catalysis of the inactivating disulfide switch in A Disintegrin and Metalloprotease 17

A Disintegrin and Metalloprotease 17 (ADAM17) can cause the fast release of growth factors and inflammatory mediators from the cell surface. Its activity has to be turned on which occurs by various stimuli. The active form can be inactivated by a structural change in its ectodomain, related to the p...

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Publicat a:Sci Rep
Autors principals: Krossa, Sebastian, Scheidig, Axel J., Grötzinger, Joachim, Lorenzen, Inken
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5773583/
https://ncbi.nlm.nih.gov/pubmed/29348576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-19429-4
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