Infection and depletion of CD4(+) group-1 innate lymphoid cells by HIV-1 via type-I interferon pathway

Innate lymphoid cells (ILCs) are severely depleted during chronic HIV-1 infection by unclear mechanisms. We report here that human ILC1s comprising of CD4(+) and CD4(-) subpopulations were present in various human lymphoid organs but with different transcription programs and functions. Importantly,...

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Publicado en:PLoS Pathog
Autores principales: Zhao, Juanjuan, Cheng, Liang, Wang, Hongbo, Yu, Haisheng, Tu, Bo, Fu, Qiang, Li, Guangming, Wang, Qi, Sun, Yanling, Zhang, Xin, Liu, Zhenwen, Chen, Weiwei, Zhang, Liguo, Su, Lishan, Zhang, Zheng
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5773236/
https://ncbi.nlm.nih.gov/pubmed/29304123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006819
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