HIV-1 infection depletes human CD34(+)CD38(-) hematopoietic progenitor cells via pDC-dependent mechanisms

Chronic human immunodeficiency virus-1 (HIV-1) infection in patients leads to multi-lineage hematopoietic abnormalities or pancytopenia. The deficiency in hematopoietic progenitor cells (HPCs) induced by HIV-1 infection has been proposed, but the relevant mechanisms are poorly understood. We report...

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Publicado en:PLoS Pathog
Autores principales: Li, Guangming, Zhao, Juanjuan, Cheng, Liang, Jiang, Qi, Kan, Sheng, Qin, Enqiang, Tu, Bo, Zhang, Xin, Zhang, Liguo, Su, Lishan, Zhang, Zheng
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2017
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5552321/
https://ncbi.nlm.nih.gov/pubmed/28759657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006505
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