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Activity of factor XII‐Locarno
ESSENTIALS: Conversion of FXII to α‐FXIIa on surfaces requires cleavage after Arginine 353. Replacing Arg353 with alanine results in a single chain form (FXII‐R353A) that has some activity. Replacing Arg‐353 with proline (FXII‐Locarno, FXII‐R353P) reduces activity of single chain FXII compared to FX...
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| Vydáno v: | Res Pract Thromb Haemost |
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| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
John Wiley and Sons Inc.
2017
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5773063/ https://ncbi.nlm.nih.gov/pubmed/29354798 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/rth2.12054 |
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