Activity of factor XII‐Locarno

ESSENTIALS: Conversion of FXII to α‐FXIIa on surfaces requires cleavage after Arginine 353. Replacing Arg353 with alanine results in a single chain form (FXII‐R353A) that has some activity. Replacing Arg‐353 with proline (FXII‐Locarno, FXII‐R353P) reduces activity of single chain FXII compared to FX...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Res Pract Thromb Haemost
Main Authors: Mohammed, Bassem M., Ivanov, Ivan, Matafonov, Anton, Emsley, Jonas, Gailani, David
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2017
Fag:
Original Articles: Haemostasis
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5773063/
https://ncbi.nlm.nih.gov/pubmed/29354798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/rth2.12054
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker