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A Survey of Validation Strategies for CRISPR-Cas9 Editing
The T7 endonuclease 1 (T7E1) mismatch detection assay is a widely used method for evaluating the activity of site-specific nucleases, such as the clustered regularly interspaced short palindromic repeats (CRISPR)-Cas9 system. To determine the accuracy and sensitivity of this assay, we compared the e...
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| Publicado en: | Sci Rep |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5772360/ https://ncbi.nlm.nih.gov/pubmed/29343825 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-19441-8 |
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