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The Swinholide Biosynthesis Gene Cluster from a Terrestrial Cyanobacterium, Nostoc sp. Strain UHCC 0450

Swinholides are 42-carbon ring polyketides with a 2-fold axis of symmetry. They are potent cytotoxins that disrupt the actin cytoskeleton. Swinholides were discovered from the marine sponge Theonella sp. and were long suspected to be produced by symbiotic bacteria. Misakinolide, a structural variant...

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Podrobná bibliografie
Vydáno v:Appl Environ Microbiol
Hlavní autoři: Humisto, Anu, Jokela, Jouni, Liu, Liwei, Wahlsten, Matti, Wang, Hao, Permi, Perttu, Machado, João Paulo, Antunes, Agostinho, Fewer, David P., Sivonen, Kaarina
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5772238/
https://ncbi.nlm.nih.gov/pubmed/29150506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.02321-17
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