The Swinholide Biosynthesis Gene Cluster from a Terrestrial Cyanobacterium, Nostoc sp. Strain UHCC 0450

Swinholides are 42-carbon ring polyketides with a 2-fold axis of symmetry. They are potent cytotoxins that disrupt the actin cytoskeleton. Swinholides were discovered from the marine sponge Theonella sp. and were long suspected to be produced by symbiotic bacteria. Misakinolide, a structural variant...

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Bibliografische gegevens
Gepubliceerd in:Appl Environ Microbiol
Hoofdauteurs: Humisto, Anu, Jokela, Jouni, Liu, Liwei, Wahlsten, Matti, Wang, Hao, Permi, Perttu, Machado, João Paulo, Antunes, Agostinho, Fewer, David P., Sivonen, Kaarina
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2018
Onderwerpen:
Environmental Microbiology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5772238/
https://ncbi.nlm.nih.gov/pubmed/29150506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.02321-17
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