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The Swinholide Biosynthesis Gene Cluster from a Terrestrial Cyanobacterium, Nostoc sp. Strain UHCC 0450

Swinholides are 42-carbon ring polyketides with a 2-fold axis of symmetry. They are potent cytotoxins that disrupt the actin cytoskeleton. Swinholides were discovered from the marine sponge Theonella sp. and were long suspected to be produced by symbiotic bacteria. Misakinolide, a structural variant...

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Dades bibliogràfiques
Publicat a:Appl Environ Microbiol
Autors principals: Humisto, Anu, Jokela, Jouni, Liu, Liwei, Wahlsten, Matti, Wang, Hao, Permi, Perttu, Machado, João Paulo, Antunes, Agostinho, Fewer, David P., Sivonen, Kaarina
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5772238/
https://ncbi.nlm.nih.gov/pubmed/29150506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.02321-17
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