The Swinholide Biosynthesis Gene Cluster from a Terrestrial Cyanobacterium, Nostoc sp. Strain UHCC 0450

Swinholides are 42-carbon ring polyketides with a 2-fold axis of symmetry. They are potent cytotoxins that disrupt the actin cytoskeleton. Swinholides were discovered from the marine sponge Theonella sp. and were long suspected to be produced by symbiotic bacteria. Misakinolide, a structural variant...

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Detalhes bibliográficos
Publicado no:Appl Environ Microbiol
Main Authors: Humisto, Anu, Jokela, Jouni, Liu, Liwei, Wahlsten, Matti, Wang, Hao, Permi, Perttu, Machado, João Paulo, Antunes, Agostinho, Fewer, David P., Sivonen, Kaarina
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Environmental Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5772238/
https://ncbi.nlm.nih.gov/pubmed/29150506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.02321-17
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