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CSF neurofilament light concentration is increased in presymptomatic CHMP2B mutation carriers

OBJECTIVE: A rare cause of familial frontotemporal dementia (FTD) is a mutation in the CHMP2B gene on chromosome 3 (FTD-3), described in a Danish family. Here we examine whether CSF biomarkers change in the preclinical phase of the disease. METHODS: In this cross-sectional explorative study, we anal...

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Bibliografiske detaljer
Udgivet i:Neurology
Main Authors: Rostgaard, Nina, Roos, Peter, Portelius, Erik, Blennow, Kaj, Zetterberg, Henrik, Simonsen, Anja H., Nielsen, Jørgen E.
Format: Artigo
Sprog:Inglês
Udgivet: Lippincott Williams & Wilkins 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5772154/
https://ncbi.nlm.nih.gov/pubmed/29237796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000004799
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