Longitudinal measurement of serum neurofilament light in presymptomatic familial Alzheimer’s disease

BACKGROUND: To investigate how serum neurofilament light (NfL) concentration changes through the course of disease in familial Alzheimer’s disease (FAD) and to assess when NfL concentration first increases. METHODS: NfL was measured using an ultrasensitive immunoassay in 117 serum samples from 61 in...

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Detalhes bibliográficos
Publicado no:Alzheimers Res Ther
Main Authors: Weston, Philip S. J., Poole, Teresa, O’Connor, Antoinette, Heslegrave, Amanda, Ryan, Natalie S., Liang, Yuying, Druyeh, Ronald, Mead, Simon, Blennow, Kaj, Schott, Jonathan M., Frost, Chris, Zetterberg, Henrik, Fox, Nick C.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6383280/
https://ncbi.nlm.nih.gov/pubmed/30786919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-019-0472-5
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