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Presymptomatic cortical thinning in familial Alzheimer disease: A longitudinal MRI study
OBJECTIVE: To identify a cortical signature pattern of cortical thinning in familial Alzheimer disease (FAD) and assess its utility in detecting and tracking presymptomatic neurodegeneration. METHODS: We recruited 43 FAD mutation carriers—36 PSEN1, 7 APP (20 symptomatic, 23 presymptomatic)—and 42 he...
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| Publicado no: | Neurology |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Lippincott Williams & Wilkins
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5109950/ https://ncbi.nlm.nih.gov/pubmed/27733562 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000003322 |
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