Protein phosphatase 5 regulates titin phosphorylation and function at a sarcomere-associated mechanosensor complex in cardiomyocytes

Serine/threonine protein phosphatase 5 (PP5) is ubiquitously expressed in eukaryotic cells; however, its function in cardiomyocytes is unknown. Under basal conditions, PP5 is autoinhibited, but enzymatic activity rises upon binding of specific factors, such as the chaperone Hsp90. Here we show that...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Nat Commun
Autors principals: Krysiak, Judith, Unger, Andreas, Beckendorf, Lisa, Hamdani, Nazha, von Frieling-Salewsky, Marion, Redfield, Margaret M., dos Remedios, Cris G., Sheikh, Farah, Gergs, Ulrich, Boknik, Peter, Linke, Wolfgang A.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5772059/
https://ncbi.nlm.nih.gov/pubmed/29343782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-02483-3
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars