Protein phosphatase 5 regulates titin phosphorylation and function at a sarcomere-associated mechanosensor complex in cardiomyocytes

Serine/threonine protein phosphatase 5 (PP5) is ubiquitously expressed in eukaryotic cells; however, its function in cardiomyocytes is unknown. Under basal conditions, PP5 is autoinhibited, but enzymatic activity rises upon binding of specific factors, such as the chaperone Hsp90. Here we show that...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nat Commun
Egile Nagusiak: Krysiak, Judith, Unger, Andreas, Beckendorf, Lisa, Hamdani, Nazha, von Frieling-Salewsky, Marion, Redfield, Margaret M., dos Remedios, Cris G., Sheikh, Farah, Gergs, Ulrich, Boknik, Peter, Linke, Wolfgang A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2018
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5772059/
https://ncbi.nlm.nih.gov/pubmed/29343782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-02483-3
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak