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Translocation of molecular chaperones to the titin springs is common in skeletal myopathy patients and affects sarcomere function

Myopathies encompass a wide variety of acquired and hereditary disorders. The pathomechanisms include structural and functional changes affecting, e.g., myofiber metabolism and contractile properties. In this study, we observed increased passive tension (PT) of skinned myofibers from patients with m...

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書目詳細資料
發表在:Acta Neuropathol Commun
Main Authors: Unger, Andreas, Beckendorf, Lisa, Böhme, Pierre, Kley, Rudolf, von Frieling-Salewsky, Marion, Lochmüller, Hanns, Schröder, Rolf, Fürst, Dieter O., Vorgerd, Matthias, Linke, Wolfgang A.
格式: Artigo
語言:Inglês
出版: BioMed Central 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5603016/
https://ncbi.nlm.nih.gov/pubmed/28915917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-017-0474-0
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