Translocation of molecular chaperones to the titin springs is common in skeletal myopathy patients and affects sarcomere function

Myopathies encompass a wide variety of acquired and hereditary disorders. The pathomechanisms include structural and functional changes affecting, e.g., myofiber metabolism and contractile properties. In this study, we observed increased passive tension (PT) of skinned myofibers from patients with m...

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Detalhes bibliográficos
Publicado no:Acta Neuropathol Commun
Main Authors: Unger, Andreas, Beckendorf, Lisa, Böhme, Pierre, Kley, Rudolf, von Frieling-Salewsky, Marion, Lochmüller, Hanns, Schröder, Rolf, Fürst, Dieter O., Vorgerd, Matthias, Linke, Wolfgang A.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5603016/
https://ncbi.nlm.nih.gov/pubmed/28915917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-017-0474-0
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