Translocation of molecular chaperones to the titin springs is common in skeletal myopathy patients and affects sarcomere function

Myopathies encompass a wide variety of acquired and hereditary disorders. The pathomechanisms include structural and functional changes affecting, e.g., myofiber metabolism and contractile properties. In this study, we observed increased passive tension (PT) of skinned myofibers from patients with m...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Acta Neuropathol Commun
Prif Awduron: Unger, Andreas, Beckendorf, Lisa, Böhme, Pierre, Kley, Rudolf, von Frieling-Salewsky, Marion, Lochmüller, Hanns, Schröder, Rolf, Fürst, Dieter O., Vorgerd, Matthias, Linke, Wolfgang A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2017
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5603016/
https://ncbi.nlm.nih.gov/pubmed/28915917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-017-0474-0
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