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Distinct TP63 isoform-driven transcriptional signatures predict tumor progression and clinical outcomes

TP63 is required to maintain stem cell pluripotency and suppresses the metastatic potential of cancer cells through multiple mechanisms. These functions are differentially regulated by individual isoforms, necessitating a deeper understanding of how the distinct transcriptional programs controlled b...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Abbas, Hussein A., Bui, Ngoc Hoang Bao, Rajapakshe, Kimal, Wong, Justin, Gunaratne, Preethi, Tsai, Kenneth Y., Coarfa, Cristian, Flores, Elsa R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5771893/
https://ncbi.nlm.nih.gov/pubmed/29180475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-17-1803
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