Distinct TP63 isoform-driven transcriptional signatures predict tumor progression and clinical outcomes

TP63 is required to maintain stem cell pluripotency and suppresses the metastatic potential of cancer cells through multiple mechanisms. These functions are differentially regulated by individual isoforms, necessitating a deeper understanding of how the distinct transcriptional programs controlled b...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Cancer Res
Autori principali: Abbas, Hussein A., Bui, Ngoc Hoang Bao, Rajapakshe, Kimal, Wong, Justin, Gunaratne, Preethi, Tsai, Kenneth Y., Coarfa, Cristian, Flores, Elsa R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5771893/
https://ncbi.nlm.nih.gov/pubmed/29180475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-17-1803
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi