Distinct TP63 isoform-driven transcriptional signatures predict tumor progression and clinical outcomes

TP63 is required to maintain stem cell pluripotency and suppresses the metastatic potential of cancer cells through multiple mechanisms. These functions are differentially regulated by individual isoforms, necessitating a deeper understanding of how the distinct transcriptional programs controlled b...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Cancer Res
Hlavní autoři: Abbas, Hussein A., Bui, Ngoc Hoang Bao, Rajapakshe, Kimal, Wong, Justin, Gunaratne, Preethi, Tsai, Kenneth Y., Coarfa, Cristian, Flores, Elsa R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5771893/
https://ncbi.nlm.nih.gov/pubmed/29180475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-17-1803
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky