Runx2 promotes both osteoblastogenesis and novel osteoclastogenic signals in ST2 mesenchymal progenitor cells

SUMMARY: We profiled the global gene expression of a bone marrow-derived mesenchymal pluripotent cell line in response to Runx2 expression. Besides osteoblast differentiation, Runx2 promoted the osteoclastogenesis of co-cultured splenocytes. This was attributable to the upregulation of many novel os...

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Pubblicato in:Osteoporos Int
Autori principali: Baniwal, S. K., Shah, P. K., Shi, Y., Haduong, J. H., DeClerck, Y. A., Gabet, Y., Frenkel, B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5771409/
https://ncbi.nlm.nih.gov/pubmed/21881969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00198-011-1728-5
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