Runx2 transcriptome of prostate cancer cells: insights into invasiveness and bone metastasis

BACKGROUND: Prostate cancer (PCa) cells preferentially metastasize to bone at least in part by acquiring osteomimetic properties. Runx2, an osteoblast master transcription factor, is aberrantly expressed in PCa cells, and promotes their metastatic phenotype. The transcriptional programs regulated by...

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Detalhes bibliográficos
Main Authors: Baniwal, Sanjeev K, Khalid, Omar, Gabet, Yankel, Shah, Ruchir R, Purcell, Daniel J, Mav, Deepak, Kohn-Gabet, Alice E, Shi, Yunfan, Coetzee, Gerhard A, Frenkel, Baruch
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2955618/
https://ncbi.nlm.nih.gov/pubmed/20863401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-258
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