Inhibition of the endocannabinoid-regulating enzyme monoacylglycerol lipase elicits a CB(1) receptor-mediated discriminative stimulus in mice

Substantial challenges exist for investigating the cannabinoid receptor type 1 (CB(1))-mediated discriminative stimulus effects of the endocannabinoids, 2-arachidonoylglycerol (2-AG) and N-arach-idonoylethanolamine (anandamide; AEA), compared with exogenous CB(1) receptor agonists, such as Δ(9)-tetr...

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Publicado en:Neuropharmacology
Main Authors: Owens, Robert A., Mustafa, Mohammed A., Ignatowska-Jankowska, Bogna M., Damaj, M. Imad, Beardsley, Patrick M., Wiley, Jenny L., Niphakis, Micah J., Cravatt, Benjamin F., Lichtman, Aron H.
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5771234/
https://ncbi.nlm.nih.gov/pubmed/28673548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2017.06.032
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